Wroxham
Irish Red And White Setters
CONTROL SCHEME FOR CLAD
(Canine Leucocyte Adhesion Deficiency)
IN IRISH RED &
WHITE SETTERS.
The following breeding control scheme
has been agreed by representatives of the Irish Red & White
Setter Breed Clubs and the Kennel Club:
From 17th June 2003 all Irish Red & White Setters used for
breeding should be either hereditarily clear of CLAD or have a
CLAD DNA test before they are used for breeding.
Identified carriers can be used for breeding, but they should
only be mated to a dog that is either hereditarily clear of CLAD
or one that has DNA tested clear of CLAD; carriers should not be
mated to carriers.
All of the registered offspring of a
carrier mated to a clear should be clearly identified, DNA
tested and registered as either tested clear or carrier.
From 17th June 2008 the Kennel Club will only register Irish Red
& White Setters that are proven clear of the CLAD mutation,
either by direct DNA testing or by virtue of having parents that
are proven to be clear of the CLAD mutation (i.e. hereditarily
clear)
No carriers will be registered after 16th June 2008.
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The following Irish Red and
White Setters have been DNA tested for Canine Leucocyte Adhesion Deficiency
(CLAD). The test distinguishes between clear, carrier and affected dogs.
Clear dogs have no copies
of the mutant gene responsible for CLAD and will neither develop the condition
nor pass a CLAD gene on to its offspring. Carrier dogs have one copy of
the normal gene and one copy of the mutant gene: they will not develop the
condition, but will pass a mutant gene on to approximately half of their
offspring. Affected dogs have two copies of the mutant gene that causes CLAD and
will develop the disease.
Follow this link for dogs
that are
carriers 
Follow this link for dogs that are clear
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